Abstract
The Covid-19 pandemic has impacted all sectors. It does not only have an impact on the economic sector but also has an impact on the education sector. Due to this situation, the teaching and learning process which is usually carried out directly in the classroom must be carried out through hybrid learning to suppress the spread of Covid-19. For this result, it is important to conduct research through hybrid learning with the aim of knowing the impact of the Covid-19 pandemic on the learning outcomes at a university using regression analysis with single and multiple predictors. The response variables used in the study were the final grades of students for certain courses, while the predictor variables were assignment scores, mid-semester examination scores, and final semester examination scores. From the modeling results, hypothesis testing can be carried out, either simultaneously or partially. Testing the hypothesis aims to determine the factors that significantly affect the final score so that the relevant tertiary institution can take policies regarding what things must be improved so that the learning process can run welland smoothly, and in accordance with the targets that have been set.