{"id":4122,"date":"2023-05-22T13:36:05","date_gmt":"2023-05-22T06:36:05","guid":{"rendered":"https:\/\/research.binus.ac.id\/bdsrc\/?p=4122"},"modified":"2023-05-22T13:36:05","modified_gmt":"2023-05-22T06:36:05","slug":"validation-of-polygenic-risk-score-prs-model-of-dnaku-skin-health-traits-for-1000-genetic-samples","status":"publish","type":"post","link":"https:\/\/research.binus.ac.id\/bdsrc\/2023\/05\/22\/validation-of-polygenic-risk-score-prs-model-of-dnaku-skin-health-traits-for-1000-genetic-samples\/","title":{"rendered":"Validation of Polygenic Risk Score (PRS) Model of DNAku Skin Health Traits for 1000 Genetic Samples"},"content":{"rendered":"<p style=\"text-align: justify\"><span style=\"font-weight: 400\">This ongoing project is a further development of the Polygenic Risk Scoring model (PRS) of 22 skin health traits targeted by BDSRC\u2019s research partner industry, PT Genetics Indonesia, for building the skin-related genetic testing module called DNAku. One of the foremost phases of the project is a data collection of 1000 genotyping samples from the Indonesian population, which is carried out by PT Genetics Indonesia.<\/span><\/p>\n<p style=\"text-align: justify\"><span style=\"font-weight: 400\">The main goal of the research is to provide a more accurate and complete statistical benchmark of the risk scoring level for those skin-related traits since some traits do not have a representative number of genetic variants to be used for the PRS. The bioinformatics analysis of the project is currently conducted by the BDSRC team. Therefore, using 1000 samples can provide a more profound genome-wide association study, especially for the Indonesian population. This is useful for population-targeted PRS models for the skin traits.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>This ongoing project is a further development of the Polygenic Risk Scoring model (PRS) of 22 skin health traits targeted by BDSRC\u2019s research partner industry, PT Genetics Indonesia, for building the skin-related genetic testing module called DNAku. One of the foremost phases of the project is a data collection of 1000 genotyping samples from the [&hellip;]<\/p>\n","protected":false},"author":7,"featured_media":4116,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11],"tags":[],"class_list":["post-4122","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-projects"],"_links":{"self":[{"href":"https:\/\/research.binus.ac.id\/bdsrc\/wp-json\/wp\/v2\/posts\/4122","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/research.binus.ac.id\/bdsrc\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/research.binus.ac.id\/bdsrc\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/research.binus.ac.id\/bdsrc\/wp-json\/wp\/v2\/users\/7"}],"replies":[{"embeddable":true,"href":"https:\/\/research.binus.ac.id\/bdsrc\/wp-json\/wp\/v2\/comments?post=4122"}],"version-history":[{"count":1,"href":"https:\/\/research.binus.ac.id\/bdsrc\/wp-json\/wp\/v2\/posts\/4122\/revisions"}],"predecessor-version":[{"id":4123,"href":"https:\/\/research.binus.ac.id\/bdsrc\/wp-json\/wp\/v2\/posts\/4122\/revisions\/4123"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/research.binus.ac.id\/bdsrc\/wp-json\/wp\/v2\/media\/4116"}],"wp:attachment":[{"href":"https:\/\/research.binus.ac.id\/bdsrc\/wp-json\/wp\/v2\/media?parent=4122"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/research.binus.ac.id\/bdsrc\/wp-json\/wp\/v2\/categories?post=4122"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/research.binus.ac.id\/bdsrc\/wp-json\/wp\/v2\/tags?post=4122"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}